What are the most common side effects of clopidogrel?
Joseph Russell
Updated on May 05, 2026
Common side effects
bleeding more easily than normal – nosebleeds, bruising more easily or bleeding that takes longer to stop. diarrhoea. stomach pain. indigestion or heartburn.What are the side effects of clopidogrel 75 mg?
Common side effects of clopidogrel can include:
- headaches or dizziness.
- nausea.
- diarrhoea or constipation.
- indigestion (dyspepsia)
- stomach ache or abdominal pain.
- nosebleeds.
- increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.
Does taking clopidogrel make you tired?
Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.How long should I take clopidogrel?
The optimal duration of dual antiplatelet therapy is not known; 12 months has been the commonly recommended duration. A recent large trial changed recommendations. Rates of stent thrombosis and death from stroke or heart attack were lower when the two meds were continued for 18 more months.What does clopidogrel do to your body?
Clopidogrel is a platelet inhibitor. It reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood. Clopidogrel may also increase the chance of serious bleeding in some people. This medicine is available only with your doctor's prescription.Clopidogrel Side Effects - What You Need To Know Now
What is the most serious adverse effect of clopidogrel?
The main side effect of clopidogrel is bleeding more easily than normal. You may have nosebleeds, heavier periods, bleeding gums or bruising. You can drink alcohol with clopidogrel.Does clopidogrel affect sleep?
The organic nitrates (isosorbide) and the antiplatelet agents (acetylsalicylic acid, clopidogrel) are among the most prescribed drugs in cardiology and are not cited as causing insomnia or sleepiness.Is there an alternative to clopidogrel?
Ticagrelor and prasugrel are antiplatelet drugs that are alternatives to clopidogrel in acute coronary syndrome. Their advantages include reduced rates of ischaemia and stent thrombosis.Is it safe to take clopidogrel long term?
Safety Announcement[ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.
How do you know if clopidogrel is working?
Talk to a pharmacist or your doctor before buying any over-the-counter medicine to check if it is compatible with clopidogrel. You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working.Do the side effects of clopidogrel go away?
Some side effects of clopidogrel may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Does clopidogrel cause shortness of breath?
Shortness of breath is not a common side effect of Plavix, but it may be symptom of a serious side effect of the drug. Plavix is used to help prevent blood clots from forming in your body. If you're taking Plavix, you were probably started on the drug because you had an increased risk of having blood clots.Does clopidogrel cause leg cramps?
It frequently occurs in the legs and often causes claudication or pain in the legs upon walking. Plavix is used to reduce the risk of heart attacks and strokes in these patients.What should I monitor with clopidogrel?
HPR while on this drug is associated with major adverse cardiovascular events. The best assays to monitor clopidogrel therapy include VerifyNow and Multiplate ADP test.What medications should not be taken with clopidogrel?
Clopidogrel may interact with other medications
- Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. ...
- Stomach acid drugs (proton pump inhibitors) ...
- Nonsteroidal anti-inflammatory drugs (NSAIDs) ...
- Blood thinners.
- Drugs used to treat depression. ...
- Salicylates (aspirin) ...
- Opioids.